In the Know: Palmitate’s influence on trophoblast viability

A new article from USDOHaD Member and Faculty Representative, Sathish Kumar Natarajan PhD, was just published in Cell Death & Disease. In their article, “Palmitate induces integrated stress response and lipoapoptosis in trophoblasts,” the researchers conducted an exploration of the effects of palmitate, a prevalent saturated free fatty acid, on placental trophoblast cell viability. Their findings reveal a concentration-dependent increase in trophoblast lipoapoptosis and the underlying mechanisms related to the MAPK pathway, highlighting the significant impact of maternal obesity on fetal development.

Read the article here!

Congratulations Dr. Natarajan on your recent publication!

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